Dr. Archana Pan
About
Research Area
I am a computational biologist. I joined the Department of Bioinformatics, Pondicherry University as an Assistant Professor in 2009. Since then, I have been offering the courses, ‘Biostatistics’, ‘Programming in Perl’ and ‘Bioinformatics: Sequence Analysis’ to M.Sc. Bioinformatics students, and ‘Mathematics for Biosciences’, ‘Fundamentals of Biostatistics’ and ‘Perl Programming for Biologists’ to M. Tech. Computational Biology students. My research group focuses on (i) discovering novel therapeutics against multi-drug resistant pathogens, (ii) characterization of unannotated genes/proteins of pathogenic significance, and (iii) dissecting metabolic pathways associated with draught response mechanisms in economically important plant species using integrated computational approaches.
I did my post graduation in Applied Mathematics at Jadavpur University, Kolkata and was awarded Ph.D. in 1998 by the same university for the work on ‘Computational analysis of statistical compositions of nucleotide sequences’. I have several years of postdoctoral experience from CSIR-Indian Institute of Chemical Biology, Kolkata and Indian Association for the Cultivation of Science, Kolkata in the field of computational biology. I had an opportunity to serve as a lecturer for a short period at Jadavpur University, Kolkata as well.
Notable & Recent Publications
Pranavathiyani G and Archana Pan, Prediction of Essential Proteins of Klebsiella pneumoniae using Integrative Bioinformatics and Systems Biology Approach: Unveiling New Avenues for Drug Discovery, OMICS: A Journal of Integrative Biology, vol 28, number 3, 2024 Mar 13. doi: 10.1089/omi.2024.0001, (IF: 3.978)
Biji Chatterjee, Krishna Ghosh, Aishwarya Swain, Kiran Kumar Nalla , Haritha Ravula , Archana Pan and Santosh R Kanade, The phytochemical brazilin suppress DNMT1 expression by recruiting p53 to its promoter resulting in the epigenetic restoration of p21 in MCF7cells, Phytomedicine, 2022 Jan; 95:153885: doi: 10.1016/j.phymed.2021.153885. (IF: 6.7)
Pranavathiyani G, Jyoti Prava, Athira CR and Archana Pan, Novel target exploration from hypothetical proteins of Klebsiella pneumoniae MGH 78578 reveals a protein involved in host-pathogen interaction, Frontiers in Cellular and Infection Microbiology, 3 April 2020, doi: 10.3389/fcimb.2020.00109, ( IF:4.6)
Jyoti Prava, Pranavathiyani G, Archana Pan, Functional assignment for essential hypothetical proteins of Staphylococcus aureus N315, International Journal of Biological Macromolecules, Oct 27, 2017, DOI: 10.1016/j.ijbiomac.2017.10.169 (IF: 7.7)
Archana Pan, Chandrajit Lahiri, Anjana Rajendiran, Buvaneswari Shanmugham, Computational analysis of protein interaction networks for infectious diseases, Briefings in Bioinformatics (2016 May), 17(3), 517-26. doi: 10.1093/bib/bbv059 (IF: 13.99)
